April 15, 2024

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Novel COVID variant JN.1 may evade vaccine immunity

2 min read

The first outbreak of coronavirus in late 2019 ravaged the world, killing millions and infecting millions. Not long ago, a new COVID variant evolved from the novel coronavirus, triggering the subsequent wave of COVID. For a number of reasons, including vaccine use and COVID guidelines, infection rates have gradually declined and the world has now recovered from COVID.

However, scientists are concerned about a new COVID variant, JN.1. This variant was first identified in Luxembourg on July 25, 2023, and has since been found in the United Kingdom, Iceland, France, and the United States.

JN.1 is completely different from other prevalent COVID strains such as XBB.5.1 and HV.1. The booster dose vaccine developed in the United States was primarily directed against the XBB.5.1 variant. However, the HV.1 variant is relatively new.

The data show that JN.1 is very different in the same spectrum compared to the Ind 2 variant, which is considered the worst variant. Notably, the HV.1 variant has an additional unique mutation. JN.1 also has a different mutation compared to XBB.5.1.

Novel COVID variant JN.1 may evade vaccine immunity

Most of the mutations occur in the spiny protein of JN.1, which may be associated with immune evasion and enhanced virulence. As a result, experts warn that current vaccines may not be able to stop the virus from spreading.

The scientists said, “Because of the mutations in its spiny protein, JN.1 appears to be more immunologically aggressive and worse than its parent. As a result, we may be at greater risk of infection.”

These differences were observed at the start of the pandemic in 2021. The scientists also noted that this was particularly evident in alpha and beta COVID.

The scientists also said that some data suggest that BA.86.1, the parent of JN.1, may be more easily transmitted than earlier variants.

However, the U.S. Centers for Disease Control and Prevention (CDC) believes the new variant will not evade vaccine immunity. The Center’s analysis is said to be based on data reconfirmed by the U.S. government’s COVID panel.

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